For the assembly of coarse-grain model of high density lipoprotein 260 CG-models of phospholipid of DPPC type and two coarse-grained threads of lipoproteins ApoAl of 920 CG-particles were taken. Common quantity of CG-particles was 4950. Quantity of CG-particles of water was 20000. Assembly was held in two stages. At the first step phospholipid core was collected. At the second step two lipoproteins belts self-twisted around phospholipid core with the subsequent formation of high-density lipoprotein.